1. Invest in a “true” 1:1 macro lens if at all possible. The closest alternatives would be the use of extension tubes (adding space between your lens and the camera) or reversing a 50mm prime lens. The later two options are able to get you to a 1:1 life-size magnification; however, at varying costs such as very close focusing distances and/or degraded image quality. Extension tubes are a cheap way to decide if macro is a style you may end up enjoying. Even if the "macro bug" bites you hard and you find yourself buying a dedicated macro prime lens, you extension tubes are still very useful.
Some popular choices for 1:1 macro lenses:Canon EF 100mm f/2.8 Macro USMThe newer Canon EF 100mm f/2.8L Macro IS USM
Canon MP-E 65mm 1-5X MacroCanon EF-S 60mm f/2.8 Macro USMCanon EF 180mm f/3.5L Macro USMNikkor 105mm f/2.8 IF-ED VR MicroSigma 105mm f/2.8 EX DG MacroSigma 150mm f/2.8 EX DG HSM APO MacroSigma 180mm f/3.5 EX DG HSM APO MacroTamron SP 90mm f/2.9 Di MacroTamro SP 180mm f/3.5 Di MacroTokina 100mm f/2.8 AF Pro Macro2. Macro photography is all about getting up close and when your camera and lens meets the subject at a magnification focus of 1:1 the depth of field will be your first hurdle to overcome. My first experience was shooting a typical house fly on some flowers and the lighting wasn’t optimal (low light). My instinct and camera told me I needed light so I opened up the aperture to its max (2.

and thought the image on the LCD looked great, once on the computer and larger screen I quickly found that most of the fly was OOF and only a sliver of the fly was in-focus. The DOF when shooting macro is very shallow and to sum this up quickly you will often have to shoot between f/8 and f/16 where the median f/11 will be use most often.
3. Flash is a heavily used tool! When you couple the fact that you are stopping down to f/8 to f/16 and certain lighting situations, you will soon realize that flash can be useful tool to use. In fact, many “good” macro photographers incorporate flash in their macro photography. Understanding flash and how it syncs with your shutter speeds can also help you “freeze” you subjects to get sharper/in-focus images. The key to using flash in macro photography is getting your flash as close to your subjects as possible and diffusing the light from the flash as best as possible. There’s tons of talk on the web, here and other places, about good techniques to use flash for macro photography.
4. When using
manual focus, a good technique involves 'rocking' the camera back and forth: set a desired magnification factor, e.g., 1:3, 1:2, 1:1 etc. on the lens scale and then 'rock' the camera into the composition until your subject's focal point goes through sharp focus and just beyond. Then 'rock' the camera back until the desired focal point is in sharp focus and release the shutter. In this manner, the already thin DOF can be 'laid over' the subject from near to far, producing an acceptably sharp single frame image.
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